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Press Releases

Actineer, a Joint Venture between ITM and CNL, appoints new President and CEO

Actineer Appoints Radiopharmaceutical Executive Joseph Oliverio as President and CEO

Chalk River, Ontario, January 16, 2025 – Actineer, a joint venture between ITM and Canadian Nuclear Laboratories (CNL) Ltd., today announced the appointment of Joseph Oliverio as President and Chief Executive Officer. With extensive industry leadership experience, Mr. Oliverio is poised to drive Actineer’s global expansion in Actinium-225 (Ac-225) production. 

January 16, 2025

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January 16th, 2025

Actineer Appoints New President and CEO

Actineer, a joint venture between ITM and Canadian Nuclear Laboratories (CNL) Ltd., today announced the appointment of Joseph...

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October 17th, 2024

Actineer Advances
Ac-225 Production

Chalk River, Ontario, October 17, 2024 – Actineer, the joint venture between ITM and Canadian Nuclear Laboratories (CNL) Ltd., has...

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December 7th, 2023

Actinium-225 production

Toronto – December 7 2023 – In support of Canadian Nuclear Isotope Council’s (CNIC) goal of ensuring a reliable supply of medical...

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October 18th, 2023

ITM and CNL Announce the Launch of Actineer

ITM Isotope Technologies Munich SE (ITM), a leading radio- pharmaceutical biotech company, and Canadian Nuclear Laboratories (CNL)

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Actineer, a Joint Venture between ITM and CNL, Advances Actinium-225 Production

Successful Cyclotron Irradiation of Ra-226 Sets the Stage for Actineer's Large-Scale Ac-225 Production for Cancer Therapies

Chalk River, Ontario, October 17, 2024 – Actineer, the joint venture between ITM and Canadian Nuclear Laboratories (CNL) Ltd., has successfully produced Actinium-225 (Ac-225) by irradiating Radium-226 (Ra-226) in a cyclotron. This production milestone achievement will enable the joint venture to provide GMP-grade Ac-225 to customers by mid-2025, alongside the submission of a US Drug Master File (DMF). 

October 17, 2024

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Actineer Quotes

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Together with ITM, CNL has already made significant process towards our goal of bringing a next-generation medical isotope to the world market. With the launch of Actineer, we are poised to establish a reliable and large-scale supply of Ac-225 that we believe will unlock ground-breaking new cancer treatments. The entire team at CNL looks forward to applying their radiochemical expertise to the development of the new production process for Actinium-225 within this joint venture.

Joe McBrearty
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Actinium-225 is a potent radionuclide utilized in targeted alpha therapies and holds great potential in the greater landscape of radionuclide therapy. Targeted alpha therapy with Actinium-225 will facilitate patient care in nuclear medicine by bringing new treatment opportunities to those who need it in addition to combining Radiopharmaceutical therapy possibilities with the established Lutetium-177. The expertise that ITM and CNL bring together is unique and essential for meeting the escalating demand for Actinium-225 across various applications.

Dr. Sebastian Marx, CBO of ITM
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Targeted alpha therapies based on Actinium-225 are gaining increasing importance in addition to the well-established beta emitters such as our highly-pure non-carrier-added (n.c.a.) Lutetium-177. Joining forces with CNL provides us the opportunity to extend our therapeutic portfolio as we continue striving to meet the needs of healthcare professionals and cancer patients worldwide.

Steffen Schuster
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It is our role to drive nuclear innovation in Canada, to bring private and public expertise together to spark these new initiatives that will ultimately benefit the health of Canadians and bring new jobs to Canada. We are building on decades of Canada’s world-leading isotope innovation, and have found the key to success is collaboration, partnership, and strong leadership. We are pleased to support the joint venture between CNL and ITM with shared values to bring this potentially lifesaving therapy to the world.

Fred Dermarkar, President and CEO of AECL
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Actineer, the joint venture between ITM and CNL, is addressing the growing and urgent global demand for Actinium-225—a rare medical radioisotope that enables the development of innovative therapies for hard-to-treat tumors. By ensuring a stable, scalable supply of this critical resource, Actineer helps to advance both clinical trials and the development of potential life-saving treatments for cancer patients worldwide.

Dr. Andrew Cavey, CEO of ITM
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Our joint venture Actineer has been launched with the overall goal to ensure access to Ac-225 as a next generation radioisotope through an innovative technology.
With the foundation of Actineer we have committed us to establish a reliable, long term and substantial production of Ac-225 in high quality standards.
This Canada based company will facilitate ground breaking research activities leading to novel cancer treatments urgently needed by many patients worldwide.

Andreas Benischke
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Two companies with long and distinguished histories of delivering medical isotopes to the global market have come together to help realize the potential that Ac-225-based radiopharmaceuticals’ promise. CNL has been fostering the Ac-225 market for years. The creation of the joint venture with ITM will accelerate advancing the technology needed to produce large quantities.

Ram Mullur
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Actineer is poised to become one of the major global suppliers of Actinium-225. I am privileged to work with such premier institutions as CNL and ITM and am eager to leverage my expertise and work together with the Actineer team to achieve this goal and thereby support the development of innovative targeted alpha radiopharmaceuticals for the treatment of challenging cancer indications.

Joseph Oliverio, President and CEO

CNIC and Actineer collaborate to strengthen Canada’s leadership in Actinium 225 production

Toronto – December 7 2023 – In support of Canadian Nuclear Isotope Council’s (CNIC) goal of ensuring a reliable supply of medical isotopes for patients and doubling Canada’s production of isotopes by 2030, CNIC is excited to welcome Actineer to its growing membership.
Formed in October 2023, Actineer is a joint venture company between Canadian Nuclear Laboratories (CNL) and ITM Isotope Technologies Munich SE (ITM). Created with the mission of fulfilling unmet global needs for Actinium-225 (Ac-225), Actineer will advance production and secure supply that will allow industrial-scale quantities of the isotope to be produced here in Canada. This will facilitate research & drug development, clinical trials, patient access to state-of-art radiopharmaceuticals and enhanced access for Canadians and cancer patients worldwide.

December 7, 2023

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